Peertechz Publications

Peertechz Journal of Pediatric Therapy Case Report Abstract  Introduction: Eventration of diaphragm is a congenital anomaly that results from a failure of muscular development of part or all of the hemidiaphragm. Clinically, eventration of diaphragm refers to an abnormal elevation of an intact diaphragm. In some cases, it may be difficult to distinguish it from congenital diaphragmatic hernia (CDH). Case Presentation: A three-week-old male, born prematurely at 30 weeks GA, who was weaned off respiratory support on the first DOL, developed respiratory distress. A chest X-ray obtained at that time when compared with the one from DOL#1 showed a new right lower lobe (RLL) opacity, suggestive of lobar atelectasis. Chest MRI revealed the “atelectatic” RLL to be the liver, raising the suspicion for CDH. Thoracoscopic evaluation revealed instead a diaphragmatic eventration, for which a plication procedure was performed. Discussion: Respiratory distress is the most common clinical manifes

International Journal of Agricultural Science and Food Technology Short Communication Abstract  The aim of the study was to eliminate the potentially harmful sulfite salts normally added to wine – based products for preservation purposes with the introduction into the wine natural products, with pronounced antioxidant activity. Frieze – dried samples taken from the plants Hippophaes and Goji Berry were added to dry white and red wines after their fermentation phase. In all sample tests the sensory and oenological characteristics remained almost unchanged compared to original samples (without the addition of natural products), although their antioxidant activity was significantly increased when leaves of the plant Hippophaes were added. Goji berry fruits and fruit of Hippophaes plant increased antioxidant activity compared to original samples.      http: //www. peertechz. com/Agricultural-Science-Food- Technology/pdf/IJASFT-1-103.pdf  

Journal of Clinical Microbiology and Biochemical Technology Research Article  Abstract  The bacterial planktonic growth and the removal of bacterial cells grown on polypropylene surface coated with covalently immobilized proteases (subtilisin Carlsberg or α-chymotrypsin) was investigated for Enterococcus hirae, Staphyloccocus epidermidis and Eschericha coli. Immobilization of both proteases on plasma-treated polypropylene was carried out using as cross-linking agent i) glutaraldehyde or ii) N’-diisopropylcarbodiimide and N-hydroxysuccinimide. In the presence of immobilized proteases a higher bacterial planktonic growth (up to 40 %) was observed. Instead, a different effect was observed on cell removal, and it varied according to the bacteria strain, the immobilized protease and the immobilization procedure. In particular, the presence of subtilisin in the polypropylene coating increased the cell removal of E. hirae by simple washing of the polypropylene surface and both subtilisi

Journal of HIV for Clinical and Scientific Research Research Article     Abstract  Background: The Government of Kenya started offering ART in the public sector since 2003. Despite the dramatic reduction in AIDS related morbidity and mortality, the emergence and spread of drug resistance (DR) threatens to negatively impact on treatment regimens and compromise efforts to control the epidemic. Therefore, there is a need for information on the situation of DR Mutations (DRMS) and their implications on treatment. Objectives: To evaluate DRMS and their implications on treatment in HIV infected individuals attending Moi Teaching and Referral Hospital (MTRH) clinics. Method: In 2009, we consecutively collected plasma samples from two groups of HIV infected individuals, antiretroviral (ARV) naive and ARV experienced for more than 12 months and failing therapy according to world health organisation (WHO) guidelines. We performed genotypic DR using well established in-house Sanger sequencin

International Journal of Dermatology and Clinical Research Case Report   Abstract  A 32-year-old man presented with a history of progressive, painful nodular growths with discharge consisting granules over the right thigh, inguinal area and right foot. Histopathological examination of the tissue biopsy was actinomycotic mycetoma. The patient showed improvement with trimethoprimsulfamethoxazole. The novelty of our case is to use Co-trimoxazole as a first line treatment modality for cases diagnosed or suspected as actinomycetoma. http: //www. peertechz. com/Dermatology-Clinical-Resea rch/pdf/IJDCR-1-109.pdf  

Archives of Community Medicine & Public Health Research Article Abstract  Objective: To develop risk adjustment models for cost evaluation in primary health care in Italy based on administrative databases. Setting: The 2007 administrative databases from the National Health Service of the Friuli Venezia Giulia Region were the data source. Data referred to the general population and included information on the use of health services (inpatient, outpatient, medication, home care) as well as on the major chronic health problems. Data included persons who, for their health condition, must not pay the contribution usually required for using health services (ticket exemption). Design: Multilevel (multivariate) statistical analysis, where the tariff of services or the price of drugs (both summed up and separated) were the dependent variables, and the health conditions and other variables related to the citizens were the predictive variables.   http: //www. peertechz. com/Community-

International Journal of Veterinary Science and Research Research Article  Abstract  The semen of rams suffers during cryopreservation, and the sperm plasma membrane breaks down during the process, creating the deleterious effect of reducing their fertilization capacity. The homeopathic medicines Medicago sativa and Aloe vera were tested to evaluate membrane protection during cryopreservation in diluent media established for the species. Semen samples from five rams were frozen in two different diluents and analyzed after thirty days of freezing. The Glycine-Yolk-Milk diluent supplemented with Medicago sativa in the twelfth Hahnemann’s centesimal potency led to decreased loss of motility and vigor of semen in rams evaluated in farms. http: //www. peertechz. com/Veterinary-Science-Researc h/pdf/IJVSR-1-102.pdf  

International Journal of Veterinary Science and Research Case Report Abstract  A two-year-old ewe was presented to Veterinary Hospital, with a sudden onset of diarrhea, epistaxis, reluctance to move and recumbency which eventually led to its death. After necropsy and tissue sample collection for further examinations, histopathological study revealed large submucosal vascular structures with some thrombotic and blood filled spaces indicator of nasotracheal cavernous hemangioma, diffuse lymphocytic enteritis, hepatic diffuse mild vacuolar degeneration, severe pulmonary hyperemia and edema, cardiac and skeletal muscle sarcocystosis with severe hyperemia and fragmentation of cardiac muscle fibers, mild perineuronal edema of the spinal cord, hyperemia and perineuronal (Purkinje cell) edema in the cerebellum, hyperemia with perineuronal and perivascular edema in the cerebrum, severe hyperemia with diffuse severe acute tubular necrosis, and mild intratubular and intrabowman’s capsular s

Archives of Community Medicine & Public Health Research Article  Abstract  Introduction: Dietary intake has a significant role in promoting health and preventing disease. Family meals have been associated with higher nutrient intake, lower obesity rates, and other social benefits, yet little is known about what influences family meal frequency. Methods: We examined psychosocial and demographic factors potentially related to eating dinner together among families of third graders (N=1474) participating in “Hi5+,” a family- and schoolbased nutrition program. Families were recruited from 33 schools to participate in a randomized trial to evaluate the efficacy of a fruit and vegetable promotion program. Results: Hierarchical sequential multiple regression identified nine independent variables that contributed significantly to predicting the frequency of family dinners. Meal-planning capability was the strongest predictor, followed by an increased number of children in the househol

Archives of Renal Diseases and Management Case Report   Case Report A 32-year-old woman presented with a one-year history of mild abdominal pain in the left upper quadrant and a palpable pulsatile abdominal mass on physical examination. The results of laboratory investigations, including serum urea and creatinine levels, were unremarkable http: //www. peertechz. com/Renal-Diseases-Management/ pdf/ARDM-1-104.pdf    

International Journal of Nanomaterials, Nanotechnology and Nanomedicine Review Article Abstract  This paper provides an insight of some of the growing number of nano-applications being researched and commercialized in nutraceuticals. Recently, number of applications in dairy and food processing, preservation, packaging and development of functional foods have become based on nanotechnology. Several critical challenges, including discovering of beneficial compounds, establishing optimal intake levels, developing adequate food delivering matrix and product formulation including the safety of the products need to be addressed. In addition the potential negative effects of nanotechnology- based delivery systems on human health need to be considered. http: //www. peertechz. com/Nanomaterials-Nanotechnolo gy-Nanomedicine/pdf/IJNNN-1-10 7.pdf

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Citlalli Garnica Assistant to the Conference Chair Aleš Horna                          Conference Chair RADANAL, Ltd., Okružní 613, 530 03 Pardubice, Czech Republic  Tel.: +420 469 779 899, Fax: +420 467 027 020, Web-page: www.radanal.cz http://www.indc.cz/en/

Journal of Clinical Research and Ophthalmology Short Communication Abstract Sensory compensation or sensory substitution occurs when a sense organ, such as the eye, is lost due to trauma or disease. Individuals often experience phantom limb sensation or pain but research increasingly points towards some individuals developing a heightened level of functioning in their remaining senses, particularly in their remaining intact eye. Losing an eye at an early age can often result in “super functioning” in the remaining eye providing that no similar trauma or disease results. Cases include young children who have undergone enucleation because of diagnosed unilateral retinoblastoma and whose remaining eye is free from disease. http: //www. peertechz. com/Clinical-Research-Ophthalm ology/pdf/JCRO-2-121.pdf

Journal of Clinical Research and Ophthalmology Research Article  Abstract Introduction: This study was conducted for evaluating and comparing levels of patient discomfort during phacoemulsification and intraocular lens implantation under topical and peribulbar anesthesia and comparative assessment of intra-operative complications. Methods: It is a hospital based comparative study on patients who underwent phacoemulsification from January’2015 to March’2015. Patients were randomly distributed to peribulbar or topical anesthesia. Parameters like age, surgery duration, blood pressure, oxygen saturation and intraoperative pain were compared in two groups. Results: 51 patients underwent phacoemulsification under topical anesthesia and 49 patients underwent phacoemulsification under peribulbar anesthesia. No statistical differences were found in surgery duration, intra-operative complications, pain, blood pressure or Oxygen saturation (SPO2). Topical group did not require additional su

Journal of HIV for Clinical and Scientific Research Research Article  Abstract Background: Human Immunodeficiency Virus (HIV) pandemic has adversely affected the nutritional status of many children in the sub region, an area where malnutrition is also endemic. The study was aimed at assessing the burden of HIV infection among under five with severe acute malnutrition, determine its common forms, the outcomes and associated co-morbidities. Method: A three year prospective study (April 2011 to March 2014) of children aged 6 weeks to 5 years with diagnosis of severe acute malnutrition was carried out in our health institution for the above objectives. Data analysis was conducted using SPSS version 16.0 software and statistical significance set at p < 0.05. Result: Of the 286 severely malnourished children studied, 142(49.2%) males, and 144 (50.3%) females, HIV sero-prevalence was 199 (69.6%, 95% CI = 63.5-76.3%) and highest in the first year of life 85(42.7%). Though uptake of pr

Journal of Vaccines and Immunology Review Article  Abstract  Expression of MHC I at the cell surface is essential for presenting peptides to circulating cytotoxic T cells. Interference with a number of components of the antigen processing machinery is an immune evasion mechanism that has been highlighted in a number of malignancies. Endoplasmic reticulum aminopeptidase 1 (ERAP1), a key component of the antigen processing pathway, undertakes the final N-terminal processing of peptide epitopes for MHC I presentation. ERAP1 acts to regulate and define the repertoire of peptides at the cell surface; changes in ERAP1 activity have significant consequences on CD8+ T cell and NK cell responses. Single nucleotide polymorphisms (SNPs) in ERAP1 have been strongly associated with a number of autoimmune conditions, viral infections and cancer. The presence of SNPs in ERAP1 significantly alter the ability to generate stable peptide epitopes for presentation, thereby altering the peptidome and

Journal of Neurology, Neurological Science and Disorders Research Article Abstract  Objective: To investigate clinical outcomes of neuromyelitis optica (NMO) patients with brain magnetic resonance imaging (MRI) abnormalities. Methods: One hundred and thirty-seven patients with NMO were enrolled. Clinical, laboratory, and MRI features were assessed and compared according to different distribution patterns of brain lesions. Results: The relapse number, Expanded Disability Status Scale (EDSS) score at initial diagnosis, and EDSS score at last visit were significantly higher in NMO patients with brain abnormalities than those in NMO patients without brain abnormalities, respectively. NMO patients with brainstem involvement had higher relapse number, EDSS score at initial diagnosis, and EDSS score at last visit than those without brain abnormalities or with only suprotentorial lesions. Conclusions: Appearance of brain abnormalities in the initial stage, especially brainstem involvemen

International Journal of Agricultural Science and Food Technology Research Article Abstract  Fenpyroximate is an effective acaricide on several food crops. In the present study, dissipation of residue of this acaricide in black tea, tea infusion and spent tea was studied. Analysis was carried out using high performance liquid chromatography with diode array detection. The rate of dissipation was found to vary with the nature of the substrate. In tea leaves the half-life of fenpyroximate ranged from 2.20 to 4.22 days. The residue of fenpyroximate was not detectable in the tea brew. http: //www. peertechz. com/Agricultural-Science-Food- Technology/pdf/IJASFT-1-102.pdf

Journal of Civil Engineering and Environmental Sciences Research Article  Abstract  Cultural barrier is always perceived as the prime challenge for modernizing idle construction markets. Unsurprisingly, most changes in construction hinge on understanding the benefits of sustainable transformation. Persistent attempts in stagnant construction cultures have materialized in some noted changes. Successful sustainable transformation in such economies appears to be chiefly impeded at the execution level. The Kotter’s model for change is globally accepted approach for comprehensive implementation of major business transformations. Modern organizational change initiatives typically embrace the notions of Six Sigma in a broader sense. This concept paper propose the use of Six Sigma DMAIC technique for reforming stagnant construction cultures. A case study from a challenged construction market is referred to for potential implication. http: //www. peertechz. com/Civil-Engineering-E

Journal of Cardiovascular Medicine and Cardiology Case Report Abstract  Infective endocarditis is a potentially fatal infectious disease which usually presents with various clinic scenarios. Although the disease generally presents itself with fever, cardiac murmur (bruit), splenomegaly and anemia; in this case we report a double valve endocarditis of a 23 years-old female patient who was admitted to our neurology clinic with acute ischemic stroke. http: //www. peertechz. com/Cardiovascular-Medicine-Ca rdiology/pdf/JCMC-2-116.pdf  

Global Journal of Medical and Clinical Case Reports Case Report  Abstract Background: Isolated fallopian tube torsion is very rare during pregnancy .The reporter’s show that the right fallopian tube torsion is most common. Most of the cases have presented in the third trimester. The diagnosis of this torsion is very difficult. There are not pathognomonic symptoms; clinical, imaging, or laboratory findings. The diagnosis is proved during the operation. Case presentation: A 29 years old G4P3L2D1RIII, 33weeks pregnant woman presented with acute colicky abdominal pain with 4 episodes of vomiting &nausea. The sonogram revealed a 2 cm exophytic mass of left ovary probably is haemorrhagic cyst. A laparotomy was performed. The ovaries were normal and there was the isolated torsion in left tube with congestion and necrose. Cesarean section and salpingectomy was performed. Conclusion: Although isolated twisted fallopian tube during pregnancy is very rare, we should Pay attention in the

Journal of Surgery and Surgical Research Research Article Abstract Background: To synthesize the concept of muscle-sparing thoracotomies for major pulmonary resections and to explore the relationship between Kraissl’s lines and skin incisions perpendicular to them. Methods: Systematic literature review was performed of MEDLINE database. Articles were selected if they described adult patients undergoing major pulmonary resection by way of a welldescribed thoracotomy that neither partially nor completely transects extra thoracic muscles, and that is independent of endoscopic instruments, and video technology. Median sternotomy was excluded. http: //www. peertechz. com/Surgery-Surgical-Research/ pdf/JSSR-1-111.pdf

Archives of Otolaryngology and Rhinology Research Article Abstract Objective: This study aimed to determine the clinical value of air- and bone-conduction auditory brainstem responses (ABRs) in children with congenital external auditory canal atresia (EACA). Methods: Air- and bone-conduction click-evoked ABRs in 38 children having congenital EACA were compared with 34 children having normal hearing. Results: ABR threshold for air and bone conduction were 66.53 ± 7.12 and 12.55 ± 6.96 dBnHL, respectively, in children with congenital EACA, as well as 25.32 ± 2.66 and 10.71 ± 4.51 dBnHL, respectively, in children with normal hearing. The two groups showed statistical difference in air-conduction ABR thresholds. Meanwhile, air–bone ABR threshold gap was greater in children with EACA than in children with normal hearing, and bone-conduction ABR wave latencies did not statistically differ between the two groups. Conclusion: Bone-conduction ABR is valuable in assessing the function of c

Archives of Clinical Gastroenterology Editorial  Editorial: One of the most important events on gastroenterology certainly was the isolation of Helicobacter pylori (H. pylori) by Barry Marshall and Robin Warren in 1983 [1], occurrence which redirected our understanding of the pathophysiology of gastrointestinal diseases. The production of urease as well as the mobility of these bacteria promoted by flagella were identified as essential factors for colonization of the gastric epithelium and, from there, within a few years, the list of H. pylori virulence factors for colonizing and persisting on the gastric surface epithelium besides some factors damaging the mucosa expanded greatly. http: //www. peertechz. com/Clinical-Gastroenterology/ pdf/ACG-1-107.pdf

International Journal of Dermatology and Clinical Research Case Report  Abstract Schamberg disease, also known as Schamberg purpura or progressive pigmentary purpura, is characterized by orange-brown or reddish-brown macules/patches with overlaying purpuric spots simulating “cayenne pepper”. We report a 54-year-old Chinese woman with Schamberg disease presenting with purpuric macules and patches of varying sizes on the ankles, legs, and knees. The lesions were nonblanchable and nonpalpable and asymptomatic. Close inspection of the lesions revealed pinpoint petechiae resembling grains of cayenne pepper superimposed on the reddishbrown macules/patches. To our knowledge, Schamberg disease has not been reported in the scientific literature in Chinese patients. http: //www. peertechz. com/Dermatology-Clinical-Resea rch/pdf/IJDCR-1-108.pdf

Journal of Neurology, Neurological Science and Disorders Research Article  Abstract  Background: Serum soluble corin was decreased not only in some cardiac diseases, but also in stroke. Cardiogenic sources play a critical role in ischemic stroke. Serum soluble corin level in stroke subtypes has not been studied. Here we aimed to study corin level in 4 stroke subtypes: hemorrhagic, thrombotic, embolic and lacunar stroke. Methods: 116 hemorrhagic stroke, 320 thrombotic stroke patients, 48 embolic stroke patients and 102 lacunar stroke patients were studied. Serum soluble corin was measured and some conventional risk factors of stroke were collected. We compared corin level among different types of stroke in men and women respectively. http: //www. peertechz. com/Neurology-Neurological-Sci ence-Disorders/pdf/JNNSD-1-102 .pdf

Journal of HIV for Clinical and Scientific Research Research Article Abstract  Background: In high-income countries, viral load is routinely used for monitoring HIV patients on antiretroviral therapy for early detection of drug failure. This is not the case in most resource limited settings like ours where only WHO immunological and clinical criteria are used for monitoring. This study is aimed at determining the rate/time of failure to 1st and 2nd antiretroviral drugs in children in our centers. Method: Is a retrospective study of children ≤18 years switched to 2nd line antiretroviral regimen and those requiring third line drugs from Jan 2006 to June 2015 in our health institution. Data analysis was conducted using SPSS version 16.0 software and statistical significance set at p < 0.05. http: //www. peertechz. com/HIV-Clinical-Scientific-Re search/pdf/JHCSR-2-114.pdf

Global Journal of Anesthesiology Case Report Abstract Objective: Opioid-induced constipation (OIC) is the most prevalent patient complaint associated with longer-term opioid use and interferes with analgesic efficacy, functionality, quality-of-life, and patient compliance. To compare effects of prolonged release (PR) oxycodone and PR naloxone (OXN), vs. PR oxycodone (OXY) vs. PR morphine (MOR) on bowel function under real-life conditions in chronic low back pain (LBP) patients with vs. those without pre-existent constipation. Research design and methods: Post-hoc analysis of data from a prospective, randomized, open-label, blinded endpoint (PROBE) streamlined study, carried out in 88 centres in Germany, where a total of 901 patients, requiring WHO-step III opioids to treat low back pain, were enrolled, and prospectively observed for 3 months. Bowel function was graded with respect to the bowel function index and characterized as normal (NCP; n=643) or constipated (COP; n=258). Tr

Journal of Civil Engineering and Environmental Sciences Research Article  Abstract Persimmon (Diospyros kaki) is grown in wide climate conditions, which may affect fruit biochemical characteristics such as vitamins, soluble solids and antioxidants. Therefore, the aim of this research is to evaluate the biochemical responses of fruit to these climate variables. For this purpose 5 districts of Kashan, Shahrud, Yazd, Kiasar and Sari were chosen to collect fruits. On November 2012, based on a complete block design ripen fruits were collected and quality factors were measured. The results of this research showed that local climate condition significantly (P < 0.01) influenced fruit biochemical characteristics. Fruit collected from Kashan had the highest vitamin C (1.74 mg /100 ml) acidity (pH = 6.6), while the samples from Shahrud had the highest soluble solids (22.13) and titratable acidity (0.04 mg/100 ml). Fruits collected from Yazd showed significant differences in Chl- and car

Peertechz Journal of Clinical Pharmacology and Clinical Pharmacokinetics Editorial   Editorial Nanoparticles are defined as structures in nanometric range - often smaller than 100 nm [1-4]. These particles can be made of sundry materials, the most common being metals, metal oxides, silicates, polymers, carbon, lipids and biomolecules. In addition, they can assume different shapes such as spheres, cylinders, platelets, tubes, etc. The study of these structures in living organisms, for diagnosis, monitoring physical and pathologic processes, therapy and control of biological systems is known as nanomedicine http: //www. peertechz. com/Clinical-Pharmacology-Clin ical-Pharmacokinetics/pdf/PJCP CP-1-102.pdf

Archives of Depression and Anxiety Research Article Abstract  Background: Depression occurs in approximately 20% of pregnant women, with up to 25% experiencing anxiety. Various pregnancy and labour complications have been associated with maternal mood problems. Methods: This population study of antenatal and early postpartum depression and maternal, child outcomes involved 649 women assessed three times: the second trimester, the third trimester, and in the early postpartum. Our objective was to determine the occurrence and outcomes on pregnancy and labour of major and mild depression. Results: Major depression in the second trimester was significantly associated with developing gestational diabetes and swelling/edema. Major depression that occurred continuously throughout pregnancy was significantly associated with induced labour and antenatal bleeding/abruption. Mild depression in the second trimester was significantly associated with antenatal bleeding/abruption and prematu

Archives of Clinical Hypertension Research Article Abstract Introduction: Hypertension control has been shown to decrease morbidity and mortality. However, it is unclear whether it is worthwhile to control blood pressure (BP) in the inpatient setting. The aim of the study was to determine physicians’ attitude towards the management and control of hypertension during hospitalization at internal medicine departments. Methods: Physicians working in general medical wards were asked to answer a questionnaire regarding their views of various aspects of hypertension control and management during hospitalization in general medical wards. Results: One hundred twenty-seven physicians responded, 58 (46%) of them estimated that 50% of their inpatients have a diagnosis of hypertension. The majority of the respondents (71, 56%) believe that high BP should not be balanced during hospitalizations. According to the physicians report most of the BP measurements were done by nurses (81%) or by n

International Journal of Clinical Endocrinology and Metabolism Review Article Abstract Hypercholesterolemia is patho-physiological condition of metabolism caused by incessant increase in blood cholesterol levels and might be a possible risk factor for many cardiovascular and its associated diseases. Due to adverse effects and cost inefficiency of medications curing hypercholesterolemic disorders, medicinal plants are providing a cost efficient alternative to reduce the risk factors. Present review is providing data of 22 important medicinal plants species possessing antihypercholesterolemic activity and their active phyto-constituents. It would provide a ready reckoner for the research related to increased cholesterol level in blood. Further efforts should be made to implement these plant based drugs in clinical trials. http: //www. peertechz. com/Clinical-Endocrinology-Met abolism/pdf/IJCEM-1-106.pdf

Journal of Surgery and Surgical Research Case Report  Anterior rectus sheath haematoma is a rare condition that typically arises from rupture of the inferior epigastric artery in patients with coagulation disorder, on anticoagulation, or after abdominal trauma. We report an unusual case of spontaneous rupture of the superior epigastric artery following a violent paroxysm of coughing in a young adult with no known coagulopathy. This case highlights the importance of radiology in clinching the diagnosis and aiding in successful conservative management with complete resolution. http: //www. peertechz. com/Surgery-Surgical-Research/ pdf/JSSR-1-110.pdf

Global Journal of Anesthesiology Review Article Abstract Therapeutic hypothermia has been advocated for neuroprotection in cardiac arrest-induced encephalopathy, neonatal hypoxic-ischemic encephalopathy, traumatic brain injury, stroke, hepatic encephalopathy, and spinal cord injury, and as an adjunct to certain surgical procedures. In this review, we address physiological mechanism of hypothermia to mitigate neurological injury, the trials that have been performed for each of these indications, the strength of the evidence to support treatment with mild/moderate hypothermia. http: //www. peertechz. com/Anesthesiology/pdf/GJA-2-1 13.pdf

Archives of Clinical Gastroenterology Review Article Abstract The current therapeutic goal in the management of chronic hepatitis B (CHB) infection is to persistently suppress hepatitis B virus (HBV) replication and prevent its progression to liver failure and the development of hepatocellular carcinoma (HCC). At present, the therapeutic strategies for CHB includes either a short course of pegylated-interferon-alfa (PEG-IFNa) and/or a long term course of nucleos(t)ide analogues (NA’s). NA’s are more preferable to PEG-IFNa, majorly for its easier route of administration and excellent tolerance and safety profiles. http: //www. peertechz. com/Clinical-Gastroenterology/ pdf/ACG-1-106.pdf

Journal of Novel Physiotherapy and Physical Rehabilitation Review Article Abstract Objective: Low back pain (LBP) represents the most prevalent and costly repercussion from musculoskeletal injury in the work place. This review examines the earlier and current research reported on the significance of physical activity on musculoskeletal injuries and LBP, the benefits and limitations of therapeutic exercise, and the potential features of various exercise modalities that may contribute to the secondary and tertiary prevention of low-back pain. http: //www. peertechz. com/Novel-Physiotherapy-Physic al-Rehabilitation/pdf/JNPPR-2- 123.pdf

Archives of Hepatitis Research Review Article Abstract In the past decade, five oral nucleos(t)ide analogs and two formulations of pegylated interferon alpha have been approved for the treatment of chronic hepatitis B (CHB). Due to low personal income and inadequate health care system, low-to-moderate genetic barrier antiviral drugs are still widely used in China, which brings increased suboptimal response, viral relapse and resistance in reallife clinical practice. Combination therapy is a relative good approach to deal with these dilemma in Chinese CHB patients, and the strategies include de novo combination, rescue combination therapy, and optimized combination therapy. At present, combination therapy could be sonsidered for those who have suboptimal response to antiviral drugs, at high risk of complications in the event of virological breakthrough/rebound, or already with drug-resistant hepatitis B virus infection http: //www. peertechz. com/Hepatitis-Research/pdf/AHR

Archives of Clinical Gastroenterology Case Report Abstract Bleeding from ectopic varices is often massive and fatal with portal hypertension, and stomal varices can occur in patients with stoma. We aimed to treat a hepatitis B surface antigen positive 69 year-old male with liver cirrhosis associated hepatocellular carcinoma with bleeding stomal varices using percutaneous injection sclerotherapy. Percutaneous injection sclerotherapy was performed under fluoroscopy using 5% ethanolamine oleate with iopamidol (EOI) with a 25 gauge disposable injection needle; 5ml of 5% EOI were injected gradually. Injection sclerotherapy controlled acute bleeding in this patient without serious complication. The patient experienced no further episodes of bleeding during the 8 months following treatment with percutaneous injection sclerotherapy. In conclusion, percutaneous injection sclerotherapy remains an option for the treatment of patients with bleeding stomal varices. http: //www. peertec

International Journal of Dermatology and Clinical Research Case Report Psoriasis with Onychodystrophy in a  7-Year-Old Boy Abstract Up to 90% of patients with psoriasis develop onychodystrophy at some point during their lives. Nail involvement precedes the skin lesions in approximately 4% of patients. We herewith report a case of a 7-year-old boy with psoriatic onychodystrophy at the age of 6 years followed by the appearance of plaque psoriasis 6 months later. The psoriatic onychodystrophy was initially misdiagnosed as onychomycosis by his family physician and was treated as such. Psoriatic onychodystrophy can clinically mimic onychomycosis and differentiation of the two conditions can be difficult. We emphasize the need for potassium hydroxide examination and culture of nail scrapings/clippings to demonstrate fungal elements, should there be doubt in the diagnosis. http: //www. peertechz. com/Dermatology-Clinical-Resea rch/pdf/IJDCR-1-107.pdf